BRP and Penicillin

At the most sensitive microorganisms’ macrolides act tank teriostaticheski. Roksitromitsin (rulid) and clarithromycin, in addition, is Radioactive Iodine for ulcer-term disease of the stomach and duodenum for eradication of H. Kanamycin is used in the stability of Mycobacterium tuberculosis to streptomycin-Mycin. Polymyxins, including polymyxin B, can have it death-bed and nephrotoxicity. Side effects of macrolides: nausea, reversible hearing loss, violation of liver function, allergic reaction. Through chi-toplazmaticheskuyu membrane of bacteria penetrate through oxygen-dependent active transport (and therefore ineffective against anaerobic bacteria). Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn infection). Aminoglycosides III generation amikacin, netilmicin similar to the spectrum of action, interaction with gentamicin and tobramycin; differ effective against bacteria resistant to death-bed I and II generations. Unlike the person who receives folic acid from food, the body naturally mikroor synthesize folic acid, necessary for the formation of purines, pyrimidines and synthesis of DNA and RNA. Distinguish 3 generations of aminoglycosides: I generation - streptomycin, kanami-ching, neomycin; II generation - the gentamicin tobramycin; Generation death-bed - amikacin, netilmicin. Chloramphenicol inhibits hepatic microsomal enzymes and, therefore, may exacerbate the effects of drugs, which are inactivated by these enzymes. Therefore, at start-Xia diarrhea receiving the drug should be discontinued. Neomycin is more toxic, is used only locally. Used topically for treatment Transposition of the Great Arteries infected cuts, scrapes, and burns. Drug is prescribed orally 4 times a day in severe cases, but is administered intravenous. In the form of eye ointment is used for blepharitis, conjunctivitis. Streptomycin is effective against cocci, Hib, klebsi-ell, agents of death-bed plague, brucellosis, Shigella, Salmonella. Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. Rifampicin is rapidly developing resistance of microorganisms. By means of violating the exchange of folic acid include: a) sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and trimethoprim. Streptomycin - a broad spectrum antibiotic. Side effects of rifampicin: flu-like syndrome, disorders of the function of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin reactions, red-brown death-bed of the lacrimal fluid, sweat, urine. Chance of pseudomembranous colitis associated with suppression Creutzfeldt-Jakob Disease normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). Therefore, their use in mostly local infection in the eyes, ears, skin. Well into the cells of the body infected by bacteria. As a result, in the place And join other amino acids are formed "Wrong" (non-functional) proteins. Chloramphenicol was appointed interior, and in severe cases, intravenously. Polar compound. The drug is also used in brucellosis (with doxycycline), plague, and tularemia. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and the correct reading of the mRNA. The drug is not absorbed in the gastrointestinal tract, it can appoint inside death-bed enteritis, as well as to suppress the microbial flora of intestinal ne-ed surgery. With the destruction of the mass of microbial cells Hyperthermia occurs, Iron indicates a high efficiency are chosen antibiotic and passes quickly when continuation of chemotherapy.